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Volume 10, Issue 2 (May 2025)
JNFS 2025, 10(2): 328-337 |
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Emrani A S, Mirjalili F, Yekrang Safakar H, Forootani B, Salehi-abargouei A. The Association between Dietary Polyphenols Intake and Risk of Liver Cancer: A Systematic Review and Meta-Analysis of Observational Studies. JNFS 2025; 10 (2) :328-337
URL: http://jnfs.ssu.ac.ir/article-1-1074-en.html
URL: http://jnfs.ssu.ac.ir/article-1-1074-en.html
Arezoo sadat Emrani 
, Fatemeh Mirjalili , Hooman Yekrang Safakar , Bita Forootani , Amin Salehi-abargouei *
, Fatemeh Mirjalili , Hooman Yekrang Safakar , Bita Forootani , Amin Salehi-abargouei *
Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract: (1008 Views)
Background: The current data on the association between dietary polyphenols intake and liver cancer are not conclusive. Therefore, we aimed to perform a systematic review and meta-analysis of observational studies on the association between dietary polyphenol intake and liver cancer. Methods: A systematic search of online databases, including PubMed/MEDLINE, Scopus, and Web of Science, was conducted until August 2024. Observational studies that investigated the association between dietary intake of polyphenols and the risk of liver cancer were included. The overall effects were assessed using the random effects model. Results: Totally, four studies were eligible to be included in the systematic review, and for meta-analysis, 3 studies with 4 effect sizes were included. The overall association between dietary intake of isoflavones and the risk of liver cancer was not significant (P=0.35, 95% CI: 0.58-1.21). Conclusion: No significant association was found between dietary polyphenols intake and liver cancer risk. Further observational studies are suggested to confirm these findings.
Type of article: review article |
Subject:
public specific
Received: 2024/05/31 | Published: 2025/05/30 | ePublished: 2025/05/30
Received: 2024/05/31 | Published: 2025/05/30 | ePublished: 2025/05/30
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