Volume 9, Issue 1 (Feb 2024)                   JNFS 2024, 9(1): 52-58 | Back to browse issues page

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Zarean E, Sadeghi P, Jafari T, Malekpour Tehrani A, Torkian S. Selenium Concentrations in Patients with Depression: A Case-Control Study. JNFS 2024; 9 (1) :52-58
URL: http://jnfs.ssu.ac.ir/article-1-621-en.html
Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Abstract:   (967 Views)
 Evidence suggests that dietary micronutrients may be associated with depression. The role of selenium as a risk or protective factor for depression was contradictory. Therefore, this study aimed to investigate the association between serum selenium concentrations and depression. Methods: This case-control study was conducted from 2018 to 2020 in Shahrekord, Iran. The case and control groups included patients with or without depression, respectively. Seventy-two participants were selected using the conventional method. In addition to recording demographic variables, the blood selenium concentration of the participants was measured. Results: There was no difference between case and control groups in terms of mean levels of blood selenium (P>0.05). Results showed that there was no statistically significant interaction between the effects of gender and group (P=0.51), age and group (P=0.13), Body mass index (BMI) and group (P=0.52) on blood selenium concentrations. However, females had significantly more selenium concentrations than males in both groups (P=0.005). Conclusion: Despite some confirming evidence for the association of depression and blood selenium concentration, this study did not show such a relationship. However, blood selenium concentration was higher in women than men in both groups.

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Type of article: orginal article | Subject: public specific
Received: 2022/04/13 | Published: 2024/02/21 | ePublished: 2024/02/21

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