Volume 8, Issue 2 (May 2023)                   JNFS 2023, 8(2): 202-211 | Back to browse issues page


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Gholami M, Ziaei S, Kazemnejad A, Movahedinejad M. The Relationship between Macronutrient Intake and Insulin Resistance in Polycystic Ovary Syndrome. JNFS 2023; 8 (2) :202-211
URL: http://jnfs.ssu.ac.ir/article-1-532-en.html
Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tehran Tarbiat Modares University, Tehran, Iran
Abstract:   (1339 Views)
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is linked to genetic and environmental factors such as nutrition. Insulin resistance (IR) is one of the major pathological changes in PCOS. This study aimed to determine the relationship between IR and macronutrient intake in PCOS subgroups. Methods: This case-control study was performed on 151 women with PCOS and were divided into four groups according to the Rotterdam diagnostic criteria: A=41, B=33, C=40, and D=37, and 31 women were also in the control group and did not have this syndrome. All macronutrients were assessed with a 168-item food frequency questionnaire (FFQ). Results: There was a significant relationship between HOMA-IR and some dietary components
 (Increased calorie in group A, increased total fat intake in group C, lower intake of unsaturated fats (PUFA and MUFA) in group D and higher intake of saturated fat (SFA) and protein intake in the control group). There was no correlation in subgroup B (ovulatory phenotype). Conclusion: Due to the significant relationship between IR and some dietary components in PCOS subtypes, it is recommended to maintain a balance in carbohydrate and fatty acids intake, and increase dietary fiber to improve health parameters in PCOS subjects.
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Type of article: orginal article | Subject: public specific
Received: 2021/12/5 | Published: 2023/05/20 | ePublished: 2023/05/20

References
1. Aali B & Naderi T 2004. Evaluation of clinical, ultrasound and laboratory features of PCOS in Kerman in 1381. Iranian journal of endocrinology and metabolism. 6: 153-161.
2. Abu-Wasel B, Walsh C, Keough V & Molinari M 2013. Pathophysiology, epidemiology, classification and treatment options for polycystic liver diseases. World journal of gastroenterology. 19 (35): 5775.
3. Asghari G, et al. 2012. Reliability, comparative validity and stability of dietary patterns derived from an FFQ in the Tehran Lipid and Glucose Study. British journal of nutrition. 108 (6): 1109-1117.
4. Azziz R, Marin C, Hoq L, Badamgarav E & Song P 2005. Health care-related economic burden of the polycystic ovary syndrome during the reproductive life span. Journal of clinical endocrinology & metabolism. 90 (8): 4650-4658.
5. Berek J 2012. Berek and Novak s gynecology, 15th ed.
6. Blüher M 2013. Adipose tissue dysfunction contributes to obesity related metabolic diseases. Best practice & research clinical endocrinology & metabolism. 27 (2): 163-177.
7. Brynes AE, et al. 2003. A randomised four-intervention crossover study investigating the effect of carbohydrates on daytime profiles of insulin, glucose, non-esterified fatty acids and triacylglycerols in middle-aged men. British journal of nutrition. 89 (2): 207-218.
8. Conway G, et al. 2014. The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. European journal of endocrinology. 171 (4): P1-P29.
9. Douglas CC, et al. 2006. Difference in dietary intake between women with polycystic ovary syndrome and healthy controls. Fertility and sterility. 86 (2): 411-417.
10. Ebbeling CB, et al. 2005. Effects of an ad libitum low-glycemic load diet on cardiovascular disease risk factors in obese young adults. American journal of clinical nutrition. 81 (5): 976-982.
11. Ehsani B, Moslehi N & Mirmiran P 2015. Effects of Hypo-caloric Ddiet and Dietary Composition on Reproductive and Metabolic Disorders in Women with Polycystic Ovary Syndrome: A Review of Studies. Iranian journal of nutrition sciences & food technology. 10 (2): 103-114.
12. ESHRE T & ASRM-Sponsored PCOS Consensus Workshop Group 2004. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertility and sterility. 81 (1): 19-25.
13. Gabrielli L & Aquino E 2012. Polycystic ovary syndrome in Salvador, Brazil: a prevalence study in primary healthcare. Gabrielli and Aquino. Reproductive Biology and Endocrinology 10 (1): 96.
14. Goodarzi M, Dumesic D, Chazenbalk G & Azziz R 2011. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nature reviews endocrinology. 7 (4): 219-231.
15. Graff SK, Mário FM, Alves BC & Spritzer PM 2013. Dietary glycemic index is associated with less favorable anthropometric and metabolic profiles in polycystic ovary syndrome women with different phenotypes. Fertility and sterility. 100 (4): 1081-1088.
16. Hashemi S, Tehrani F, Noroozzadeh M & Azizi F 2014. Normal cut-off values for hyperandrogenaemia in Iranian women of reproductive age. European journal of obstetrics & gynecology and reproductive biology. 172: 51-55.
17. Hernández-Valencia M, Hernández-Rosas M & Zárate A 2010. Care of insulin resistance in polycystic ovary syndrome. Ginecologia y obstetricia de Mexico. 78 (11): 612-616.
18. Homayounfar R, et al. 2013. Diet-induced metabolic syndrome model in rats. Journal of Fasa University of medical sciences. 2 (4): 288-296.
19. Hosseini-Esfahani F, et al. 2015. Interaction of APOC3 polymorphism and dietary fats on the risk of metabolic syndrome. Iranian journal of endocrinology and metabolism. 16 (5): 345-355.
20. Kar S 2013. Anthropometric, clinical, and metabolic comparisons of the four Rotterdam PCOS phenotypes: A prospective study of PCOS women. Journal of human reproductive sciences. 6 (3): 194-200.
21. Kasim-Karakas SE, et al. 2004. Metabolic and endocrine effects of a polyunsaturated fatty acid-rich diet in polycystic ovary syndrome. The Journal of Clinical Endocrinology & Metabolism. 89 (2): 615-620.
22. Kauffman RP, Baker VM, DiMarino P, Gimpel T & Castracane VD 2002. Polycystic ovarian syndrome and insulin resistance in white and Mexican American women: a comparison of two distinct populations. American journal of obstetrics and gynecology. 187 (5): 1362-1369.
23. Kim HM, Park J, Ryu SY & Kim J 2007. The effect of menopause on the metabolic syndrome among Korean women: the Korean National Health and Nutrition Examination Survey, 2001. Diabetes care. 30 (3): 701-706.
24. Legro RS, et al. 2013. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. Journal of clinical endocrinology & metabolism. 98 (12): 4565-4592.
25. Matthews D, et al. 1985. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 28 (7): 412-419.
26. McLaughlin T, et al. 2016. Adipose cell size and regional fat deposition as predictors of metabolic response to overfeeding in insulin-resistant and insulin-sensitive humans. Diabetes. 65 (5): 1245-1254.
27. Mirmiran P, Esfahani FH, Mehrabi Y, Hedayati M & Azizi F 2010. Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public health nutrition. 13 (5): 654-662.
28. Moran L, et al. 2013. The contribution of diet, physical activity and sedentary behaviour to body mass index in women with and without polycystic ovary syndrome. Human reproduction. 28 (8): 2276-2283.
30. Panagiotakos DB, et al. 2005. The relationship between dietary habits, blood glucose and insulin levels among people without cardiovascular disease and type 2 diabetes; the ATTICA study. Review of diabetic studies. 2 (4): 208.
31. Pehlivanov B & Orbetzova M 2007. Characteristics of different phenotypes of polycystic ovary syndrome in a Bulgarian population. Gynecological endocrinology. 23 (10): 604-609.
32. Ramezani F, Rashidi H & Azizi F 2011. The prevalence of idiopathic hirsutism and polycystic ovary syndrome in the Tehran Lipid and Glucose Study. Reproductive biology and endocrinology. 9: 144.
33. Saidpour A, et al. 2011. Effects of high-fat diets based on butter or soybean, olive or fish oil on insulin resistance and plasma desacyl-ghrelin in rats. Iranian journal of nutrition sciences & food technology. 6 (3): 39-48.
34. Schorge J, et al. 2008. Williams gynecology. McGraw-Hill Medical New York.
35. Sjaarda LA, et al. 2015. Dietary carbohydrate intake does not impact insulin resistance or androgens in healthy, eumenorrheic women. Journal of clinical endocrinology & metabolism. 100 (8): 2979-2986.
36. Stender S & Dyerberg J 2004. Influence of trans fatty acids on health. Annals of nutrition and metabolism. 48 (2): 61-66.
37. Tehrani F, Rashidi H, Khomami M, Tohidi M & Azizi F 2014. The prevalence of metabolic disorders in various phenotypes of polycystic ovary syndrome: a community based study in Southwest of Iran. Reproductive biology and endocrinology. 12 (1): 1-6.
38. Thomson R, et al. 2009. The effect of weight loss on anti-Müllerian hormone levels in overweight and obese women with polycystic ovary syndrome and reproductive impairment. Human reproduction. 24 (8): 1976-1981.
39. Tierney AC & Roche HM 2007. The potential role of olive oil‐derived MUFA in insulin sensitivity. Molecular nutrition & food research. 51 (10): 1235-1248.
40. Wallace T, Levy J & Matthews D 2004. Use and abuse of HOMA modeling. Diabetes care. 27 (6): 1487-1495.
41. Williams C 1995. Macronutrients and performance. Journal of sports sciences. 13 (51): s1-s10.
42. XIA HX & ZHANG W 2012. Study of Association between Polycystic Ovary Syndrome and Dietary Intake. Journal of reproduction & contraception. 23 (1): 29-40.
43. Zangeneh F, Naghizadeh M, Bagheri M & Jafarabadi M 2017. Are CRH & NGF as psychoneuroimmune regulators in women with polycystic ovary syndrome? Gynecological endocrinology. 33 (3): 227-233.
44. Zhang J, et al. 2015. High intake of energy and fat in Southwest Chinese women with PCOS: a population-based case-control study. PloS one. 10 (5): e0127094.
45. Zivkovic AM, German JB & Sanyal AJ 2007. Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease. American journal of clinical nutrition. 86 (2): 285-300.

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