Volume 8, Issue 2 (May 2023)                   JNFS 2023, 8(2): 158-162 | Back to browse issues page


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Artoonian V, Aghamollaii V, Nadjarzadeh A, Bidaki R. Onset of Mania by Vitamin B12 Injection in a 52-Year Old Patient with Refractory and Resistant Depression. JNFS 2023; 8 (2) :158-162
URL: http://jnfs.ssu.ac.ir/article-1-443-en.html
Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd , Iran
Abstract:   (1745 Views)
Vitamin B12 affects and modify the function of multiple organ systems. Its deficiency may cause psychiatric symptoms in addition to hematologic, gastrointestinal, and neurologic manifestations. The present case study aims to report  a patient with vitamin B12 deficiency who coexisted with resistant and persistent depression, and experienced mania phase after the replacement of vitamin B12. For a patient with refractory and resistant depression  and evidence or a risk factor for vitamin B12 deficiency, it is required to check plasma levels and monitor psychiatric symptoms during vitamin B12 supplementation. There are some manifestations of B12 deficiency including bipolar disorder, mood lability, irritability, and psychosis due to deficiency but  we  didn’t  find  case  report  about  induce  of  psychiatric  presentation follow   correction  of  vitamin B12  deficiency
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Type of article: case reports | Subject: public specific
Received: 2021/07/10 | Published: 2023/05/20 | ePublished: 2023/05/20

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