Volume 6, Issue 4 (Nov 2021)                   JNFS 2021, 6(4): 374-382 | Back to browse issues page

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Fallahzadeh H, Momayyezi M, Mirzaei M. Reference Values for Serum Lipid Profiles in Iranian Adults: A Spline-Based Quantile Regression Method. JNFS. 2021; 6 (4) :374-382
URL: http://jnfs.ssu.ac.ir/article-1-425-en.html
Deptartment of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (541 Views)
Background: Reference measurements are used to screen for abnormal blood lipids. The problem is that these reference values obtained in one population cannot be effective for another population. This study aimed to determine the reference values for blood lipids profiles in the population aged 25-64 years in Yazd. Methods: This descriptive study was based on the data of  Yazd Health Study (YaHS) on 3800 adults by cluster sampling. The data set included gender, age, total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), and  high-density lipoprotein-cholesterol (HDL-C). The linear percentile regression model and the generalized additive model for location, scale, and shape (GAMLSS) were fitted to the data and the reference values were predicted according to the regression coefficients. R-3.0.1 software was used for data analysis. Results: Refrence values for TC, LDL-C, and HDL-C were 109.43-275.72, 45.58-177.70, and 29.95-62.22 mg/dl. The trend of TC, TG, and LDL-C levels increased with age in both genders, but the trend of HDL-C in men decreased with age and remained almost constant in women. Conclusion: In this study, for the population of Yazd, reference values for blood lipids were different in both genders and age groups. Reference values for lipid profile increased in men and women with age.These findings can be used in both prevention and clinical decisions.
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Type of article: orginal article | Subject: public specific
Received: 2021/06/13 | Accepted: 2021/07/20 | Published: 2021/11/10 | ePublished: 2021/11/10

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