Volume 9, Issue 4 (Nov 2024)                   JNFS 2024, 9(4): 702-711 | Back to browse issues page

‎ 10.18502/jnfs.v9i4.16899

XML Print

Relationship between Diet-Related Inflammation and Hospitalization Risk and Disease Severity in Patients with COVID-19
Zahra Yari * , Samira Ebrahimof , Samira Soltanieh , Marieh Salavatizadeh , Sara Karimi , Sussan K. Ardestani , Mohammadreza Salehi , Soodeh Razeghi Jahromi , Tooba Ghazanfari , Azita Hekmatdoost
Department of Nutrition Research, National Nutrition and Food Technology Research Institute and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (778 Views)
Increased serum concentrations of inflammatory biomarkers in patients indicate a strong association between COVID-19 and inflammation. However, the association between diet-related inflammation and COVID-19 has been less investigated. The aim of this study is to investigate whether the inflammatory scores of the diet are associated with the severity of COVID-19 disease and the probability of hospitalization of patients.  Methods: The authors conducted a cross-sectional study involving 141 patients with COVID-19. The empirical dietary inflammatory pattern (EDIP) and dietary inflammation scores (DIS) were calculated based on a 147-item semi-quantitative food frequency questionnaire. The association between serum levels of inflammatory biomarkers and diet-related inflammation was also investigated. Results: 74 inpatients and 87 outpatients participated in this study. Higher DIS scores were significantly associated with an increased risk of COVID-related hospitalization (Tertile3 vs. tertile1: OR = 3·62; 95 % CI 1·43 to 9·14, P=0·008 after fully adjustment). This association with EDIP was also observed, but it was not significant. Conclusion: The data from this provide evidence that a pro-inflammatory diet was associated with higher risk of hospitalization due to high severity of COVID-19
Keywords: COVID-19, Inflammation, Diet, Infections, Biomarkers.
Full-Text [PDF 732 kb]   (162 Downloads) |   |   Full-Text (HTML)  (59 Views)  
Type of article: orginal article | Subject: public specific
Received: 2023/01/7 | Published: 2024/11/20 | ePublished: 2024/11/20
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.