Volume 5, Issue 2 (May 2020)                   JNFS 2020, 5(2): 109-117 | Back to browse issues page


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Sangsefidi Z S, Norouzy A, Safarian M, Kashanifar R, Pourbaferani R, Ghafouri-Taleghani F, et al . The Association between Dietary Intakes and Differentiated Thyroid Cancer: A Cross-Sectional Study among Patients and Healthy People in Iran. JNFS. 2020; 5 (2) :109-117
URL: http://jnfs.ssu.ac.ir/article-1-206-en.html
Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:   (695 Views)
Background: Differentiated thyroid cancer (DTC) is the most prevalent endocrine cancer. Evidence showed a significant association between diet and DTC. Thus, this study aimed to assess the relationship between dietary intakes and DTC. Methods: This case-control study was accomplished among 300 adult patients and 300 matched (age and gender) controls in Mashhad city, Iran. Dietary assessment was conducted and the relationship between dietary intakes and DTC were examined by a validated food-frequency questionnaire and logistic regression analysis, respectively. Results: After adjusting for the confounders, a protective effect was observed for the highest tertile of low-fat dairy (OR=0.3, 95% CI=0.17-0.53, P < 0.001) and fruits' intakes (OR=0.28, 95% CI=0.15-0.52, P < 0.001) on DTC. However, the highest tertile of sugar intake was significantly related to greater DTC ch