Volume 4, Issue 2 (May 2019)                   JNFS 2019, 4(2): 126-141 | Back to browse issues page


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Sakhaei R, Talenezhad N, Mohammadi M, Ramezani-Jolfaie N. Vitamin D Food Fortification is an Effective Approach for Improving Vitamin D Status; A Systematic Review . JNFS. 2019; 4 (2) :126-141
URL: http://jnfs.ssu.ac.ir/article-1-256-en.html
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (396 Views)
Background: Low vitamin D (vit D) serum levels have been linked to various diseases such as multiple sclerosis, cardiovascular diseases, and diabetes. Maintenance of optimal vit D level should be supported by foods and supplements. Limited food sources of vit D made researchers focus on food fortification in recent years. Methods: A systematic review of randomized controlled trials reporting the impact of vit D food fortification on 25-hydroxy vitamin D [25(OH)D] level was conducted on PubMed, Scopus, ISI Web of Science and Google Scholar from inception up to August 2017. Results: Sixteen studies met the inclusion criteria and most of them (n =14) have represented the significant effect of food fortification on the improvement of vit D status of the participants. However, two studies failed to find any reasonable associations. Furthermore, it was observed that vit D food fortification has a greater impact on the people with lower 25(OH)D serum levels. Conclusions: Fortification of foods with vit D has a significant impact on serum 25(OH)D concentrations. Therefore, food enrichment is an economical and effective approach for different populations to prevent vit D deficiency.
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Type of article: review article | Subject: public specific
Received: 2018/04/10 | Accepted: 2018/08/14 | Published: 2019/05/1

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