en jalali 1404 2 1 gregorian 2025 5 1 10 2 online 1 fulltext

en Background:  Behçet's disease (BD) with autoimmune and auto-inflammatory nature is more prevalent in Silk Road countries. The current study aimed to investigate the effect of zinc gluconate supplementation on C-reactive protein (CRP) and malondialdehyde (MDA) levels in BD patients. Methods: This randomized controlled clinical trial was conducted on 50 Iranian BD patients. Participants were randomly assigned into either placebo or zinc gluconate (30 mg/day) groups for 12 weeks. Before and after the intervention, serum MDA and CRP levels were measured. Results: Zinc supplementation led to a significant increase in serum zinc levels compared to the placebo group (P<0.05). There was no significant difference in MDA serum levels between the groups after adjusting for the baseline values and confounding factors (P>0.05). Zinc supplementation led to a significant improvement in CRP serum levels compared to the placebo group following adjustment for the effect of baseline values and confounding factors (P=0.012 and 0.04, respectively). Conclusion: Zinc supplementation in an elemental dose of 30 mg per day has an anti-inflammatory effect in BD patients by reducing CRP levels. The beneficial effect of zinc on lipid peroxidation in BD patients was not shown in the study.   Malondialdehyde, Zinc, CRP, Behcet disease. 194 203 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-257-2&slc_lang=en&sid=1 2024/05/17 1403/2/28 2024/09/21 1403/6/31 Amir Hossein Faghfouri Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran Amir.nut89@gmail.com No Seyyed Morteza Seyyed Shoura Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran Shouramor@gmail.com No Ghazaleh shahhosseini Department of Dentistry, Islamic Azad university, Tehran, Iran Ghh1378@gmail.com No Amir Arshia Khodabandehloo 4Department of Converging Sciences and Technologies, Islamic Azad University Science and Research Branch ,Tehran, Iran Arshiyakhodabandehloo.srbia@gmail.com No Pourya Fathollahi Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran No Alireza Khabbazi Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Khabbazi@gmail.com No Vali Musazadeh Student research committee, School of Public Health, Iran University of Medical Sciences, Tehran, Iran mosazadeh.vali05@gmail.com No Beitullah Alipour Department of Community Nutrition, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran alipourb@tbzmed.ac.ir Yes

en Background: Dietary Acid Load (DAL) is the balance between acid-producing and base-producing food. Previous studies have assessed the association between DAL and the risk of several cancers.  However, few studies have investigated the association between DAL and Gastric Cancer (GC) risk. The current study was carried out to evaluate the association between DAL and GC risk in Iran. Methods: The current case-control study was conducted on 184 patients newly diagnosed with GC and 276 healthy controls.  A validated diet history questionnaire (DHQ) was applied to assess dietary intake. DAL was calculated by computing amounts of protein intake into potassium contents through net endogenous acid production (NEAP) method. Multi-adjusted logistic regression was used to define the association between DAL and GC risk. Results: The mean age of participants was 56.26 years. Intakes of energy, dietary fiber, zinc, selenium, grain, fruits, and vegetables were significantly lower, and protein intake was significantly higher in the case group compared to the control group. A direct association was observed between DAL and GC risk (OR=4.59; 95% CI:2.61-8.07; P-trend<0.001, for T2 versus T3). In the fully adjusted model, DAL was positively associated with the risk of GC (OR=3.55; 95% CI:1.89-6.99; P-trend<0.001). Conclusion:  Higher DAL scores were directly associated with greater GC odds which supports the current recommendations for decreasing the risk of cancer incidence. Diet, Stomach cancer, Iran, Dietary acid load. 204 214 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1138-1&slc_lang=en&sid=1 2024/05/172024/06/9 1403/3/20 2024/09/212024/09/21 1403/6/31 Farimah Dehghani Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran farimahdehghani1998@gmail.com 0009-0005-3814-8945 No Fatemeh Toorang Departments of Medical and Surgical Sciences, University of Bologna, Italy f.toorang@gmail.com 0000-0002-1969-4749 No Bahareh Sasanfar Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran b.sasanfar@yahoo.com 0000-0002-9560-1049 No Saba Narmcheshm Cancer Research Center, Cancer Institute, Tehran University of Medical Science, Tehran, Iran sb.narmcheshm@gmail.com 0000-0003-3277-6041 No Maryam Hadji A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio 70150, Finland mrym.hadji@gmail.com 0000-0001-5486-7513 No Kazem Zendehdel Cancer Biology Research Center, Cancer Institute, Tehran University of Medical Science, Tehran, Iran kzendeh@gmail.com 0000-0002-0269-4945 No Ahmad Esmaillzadeh Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran a.esmaillzadeh@gmail.com 90000-0002-8735-6047 Yes

en Background: The perception of body weight seems to have an impact on weight-control behaviors and is associated with an increased risk of eating disorders EDs). The study aims to examine the perceptions of body weight, anthropometric characteristics, and the risk of EDs in female students in Zanjan, Iran. Methods: Using a cross-sectional design, the data of 359 students aged 16-19 year attending secondary high schools in Zanjan, during the school year 2017-2018 were collected and analyzed. Results: The results revealed a significant association between being overweight and having obese body shape, high levels of stress, and the odds of EDs. Additionally, there was a significant inverse relationship between being overweight and obese body mass index (BMI), overweight and obese body shape, and the odds of oral control subscale of EDs. Conclusion: The results of this study demonstrated a relationship between BMI, stress level, body shape, and an elevated risk of EDs. Further prospective studies are needed to validate and expand upon these findings. Eating disorders, Body image, Body mass index, Obesity, 215 226 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-898-2&slc_lang=en&sid=1 2024/05/172024/06/92024/10/28 1403/8/7 2024/09/212024/09/212025/02/15 1403/11/27 Sara Mohiti Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran saramohitinutr@yahoo.com 0000-0002-8795-467X No Safa Sefidgari-abrasi Department of Nutrition, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran Safa.sefidgari@gmail.com 0000-0003-2475-9073 No Saba Mohiti Department of Biochemistry and Nutrition, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran sabamohitinutr@yahoo.com 0000-0003-4253-2526 No Shahram Arsang-Jang Department of Biostatistics and Epidemiology, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran shahramarsang@gmail.com 0000-0001-7476-0414 No Ahmadreza Rasouli Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran ahmadrasoulinut@yahoo.com 0000-0003-4037-8393 Yes

en Background: Increased consumption of fat and sugar has been linked to obesity and diseases like non-alcoholic fatty liver disease (NAFLD). Lycopene (LYC), an antioxidant, has been studied for its potential in protecting against fatty liver damage. This study aims to investigate how lycopene affects the antioxidant system and the expression of the adiponectin gene in rats with fatty liver disease. Methods: Wistar rats were divided into three groups: control, n=8), high fat diet (HFD, n=8), and lycopene (HFD+LYC, n=8). The lycopene group received a solution containing 100 mg/kg of lycopene three days a week, while the other groups received standard food for eight weeks via gavage. The levels of adiponectin gene expression in the liver were assessed using the real time PCR method. Additionally, the levels of antioxidant enzymes in the serum were measured using ELISA. Results: Although lycopene did not have a significant therapeutic effect on malondialdehyde (MDA) compared HFD group (P=0.6103), it improved the levels of the SOD enzyme and the expression of the adiponectin gene compared with HFD group (P=0.0002, P=0.0001). This was a significant decrease in collagen deposition in liver tissue of HFD+LYC group compared to HFD group (P<0.0001). Conclusion: Lycopene demonstrates the potential as a therapeutic option for NAFLD. However, more trials are needed to support this idea. SOD, MDA, Lycopene, Liver, Antioxidant, Adiponectin, Non-alcoholic fatty liver disease, Oxidative stress. 227 235 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1168-2&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/7 1403/6/17 2024/09/212024/09/212025/02/152024/12/12 1403/9/22 Nastaran Amini Department of Physical Education, Faculty of Literature, Humanities and Social Sciences, Islamic Azad University Science and Research Branch, Tehran, Iran nastaranamini1214@gmail.com 0009-0002-0819-7808 No Mandana Gholami Department of Physical Education and Sport Sciences, Faculty of Literature, Humanities and Social Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran gholami_man@yahoo.com 0000-0001-8960-4123 Yes Seyyedmostafa Seyyedashour Department of Physical Education, Faculty of Literature, Humanities and Social Sciences, Islamic Azad University Science and Research Branch, Tehran, Iran scholarly.smostafa@gmail.com 0009-0008-1518-3627 No Mansour Shoae Department of Physical Education, Faculty of Literature, Humanities and Social Sciences, Islamic Azad University Science and Research Branch, Tehran, Iran mansourshoae.research@gmail.com 0009-0001-0738-3820 No

en Background: Snacks mainly from street food, provide 20–31.1 percent of the energy that students need per day. Street food refers to ready-to-eat food and beverages prepared and served in public areas. In contrast, street food vendors frequently add hazardous substances such as formalin and borax, as well as cyclamate, rhodamine B, and methanyl yellow, which can be harmful to students' health. This study aimed to observing the current condition of street food vendors surrounding the schools in Semarang city. Methods: This was an observational study selected by consecutive sampling. Street food samples were collected from 37 schools in Semarang city, Indonesia. The hazardous substances such as formalin, borax, methanyl yellow, and cyclamate were qualitatively tested using easy testing kits. Result: This study showed that 78.3% of the street food samples had formalin, 19.1% contained rhodamin B, 3.3% included methanyl yellow, and 4.0% contained cyclamate. Conclusion: Street food has a high ratio of preservatives (formalin). Therefore, it is necessary to regulate the sale of street food, especially those containing hazardous food additives. Food security, Street food, Students, Indonesia 236 243 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1045-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/29 1402/10/8 2024/09/212024/09/212025/02/152024/12/122024/09/21 1403/6/31 Gemala Anjani Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia gemaanjani@gmail.com 0000-0002-7774-7693 Yes Ahmad Syauqy Center of Nutrition Research, Integrated Laboratory for Research and Services, Diponegoro University, Semarang, Indonesia syauqy@fk.undip.ac.id 0000-0002-9552-2834 No Fitriyono Ayustaningwarno Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia ayustaningwarnofk.undip.ac.id 0000-0003-2409-5449 No Etika Ratna Noer Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia etikaratna@fk.undip.ac.id 0000-0002-1555-5944 No Nur Atmilati Khusna Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia atmilati@gmail.com No Nadia Budi Pratiwi Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia nadiabudipratiwi@gmail.com No Zulfatul Masruroh Department of Nutrition Science, Faculty of Medicine, Diponegoro University, Semarang Indonesia Masrurohzulfatul@gmail.com 0009-0009-2080-6945 No

en Background: Obesity is a major public health problem among children and has emerged as a significant public health challenge in the 21st century. It is associated with the risk of complications in childhood and increased morbidity and mortality in adulthood. This study investigated the prevalence of overweight and obesity in children aged 6-12 years in Yazd, Iran in 2022. Methods: This cross-sectional study examined 6353 children using cluster sampling to determine the prevalence of obesity among 6-12 years students. Results: A total of 654 (9.86%) and  350 (5.50%)  of children were obes and overweight, respectively. From  3098 boys, 113 (3.64%) were overweight and 331 (10.68%) were obese. Among 3255 girls, 237 (7.28%) of them were overweight and 323 (9.92%) were obese. Girls were almost twice as likely to be overweight, while there was no significant difference in obesity between boys and girls. Conclusion: A significant increase in obesity among primary school students in recent years was observed. Obesity, Overweight, Children, Yazd.. 244 247 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1185-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/6 1403/8/16 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/21 1401/12/2 Naser Ali Mirhosseini Department of Pediatrics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran No Hossein Lojje Department of Pediatrics, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran hosseinlojje@yahoo.com No Forouzan Emaeili Dahaj Stem Cell Biology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran forouzan.emaeili.dahaj@gmail.com Yes Seyedeh Mahdieh Namayandeh Research Center of Statistical Modeling of Health Care Data, Afshar Hospital Research Development Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran No

en Background: Obesity is associated with a chronic low-grade inflammatory state related with vascular dysfunction, thrombotic disorders, multiple organ damages, and metabolic dysfunction. To date, no study has examined the effects of different exercise protocols on the profile of inflammatory factors in the body and the use of dietary supplements. The objective of this study was to investigate the effect of 12 weeks of high-intensity functional training (HIFT) with and without thylakoid supplementation on IL-10 and semaphorin-3E levels in obese people. Methods: 44 obese men were randomly assigned to one of four groups: control (C), thylakoid supplementation (T), high-intensity functional training (H), and a combination of supplementation and exercise (HT). The exercise program was performed according to the HIFT protocol for 12 weeks. The thylakoid supplement was extracted from spinach leaves and administered to individuals in the supplement groups. Body mass index (BMI) and biomarkers related to inflammation were measured in the participants' blood samples at the before and after the intervention. Results: In these three groups, H, T, and HT, the levels of the inflammatory factors IL-10, and Semaphorin-3E were compared. In all the three groups, the levels of the anti-inflammatory factor Semaphorin-3E and IL-10 changed significantly (P<0.001 vs. C). The level of Semaphorin-3E exhibited a statistically significant decline in the blood of the H and HT groups who underwent exercise in comparison to the C group (P<0.01) and a significant difference was observed between the exercise training groups, H and HT, and T group (P<0.001). Conclusion: The results of the present study demonstrated that HIFT exercise protocol and the use of thylakoid supplements can reduce systemic inflammatory indicators in obese men. This reduction was observed through a synergistic effect. Consequently, the combination of HIFT exercise and thylakoid supplements represents an effective approach to reducing inflammation in individuals with obesity. Obesity, Exercise therapy, Anti-inflammatories, Weight reduction, Nutritional and metabolic diseases. 248 258 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1130-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/30 1403/3/10 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/21 1403/7/30 Heidar EbadiAsl Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, Iran h.ebadi@ut.ac.ir No Bahman Mirzaei Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, Iran mirzaei@united-world-wrestling.org Yes Arsalan Damirchi Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, Iran damirchi@guilan.ac.ir No

en Background: Type 2 diabetes mellitus (T2DM) is a prevalent and intricate disease globally. Despite various available treatments, there is no cure for it, and it is still associated with significant socioeconomic challenges. Small molecules with antioxidant activity and stabilizing effect on protein structure piqued our interest as potential antiglycating agents to decrease diabetes complications. Thus, this study aimed to evaluate and compare the antioxidant potential of Crocin with saffron aqueous extract (SAE) and two polyols (Glycerol and Myoinositol) in T2DM rats. Method: Neona­­­­­­tal male Wister rats were randomly divided into two groups. Diabetic groups at 3-5 days of birth received streptozotocin (STZ) (90 mg/kg) via intraperitoneal injection. After eight weeks, both groups were divided into subgroups and treated with SAE, Crocin, Glycerol, or Myoinositol. After five months, rats were sacrificed and their serum oxidative parameters and liver antioxidant enzymes were evaluated. Result: Crocin (100 mg/kg) significantly decreased advanced glycation end products (AGEs) and increased ferric reducing ability of plasma (FRAP) in serum of diabetic rats. Moreover, the reduction in liver catalase and superoxide dismutase specific activities, as well as glutathione (GSH) concentration in diabetic rats’ liver significantly increased after treatment with the same amount of Crocin. There were no significant changes in advanced oxidation protein products (AOPP) and Nitric Oxide (NO). Conclusion: Among the mentioned treatments, Crocin at 100 mg/kg was more effective than SAE, Glycerol, and Myoinositol in decreasing AGEs, increasing serum antioxidant capacity, and increasing the activity of hepatic antioxidant enzymes and GSH. Type 2 diabetes, Saffron Streptozotocin, FRAP, Oxidative stress, Crocin, Glycerol, Myoinositol, Diabetic rat. 259 271 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1249-2&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/9 1403/8/19 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/21 1403/11/2 Matin Mohyadini Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran matin.mhy@gmail.com 0009-0003-7535-5391 No Saeed Shirali Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran zbatha2000@yahoo.com 0000-0001-7294-982X No S. Zahra Bathaie Institute for Natural Products and Medicinal Plants (INPMP), Tarbiat Modares University, Tehran, Iran. zbatha2000@yahoo.com 0000-0002-2529-045X Yes

en Background: Momordica charantia (bitter melon) is commonly used in traditional medicine for the management of diabetes, due to its insulin-like properties. This study was conducted to assess the effectiveness of bitter melon powder in managing Type 2 diabetes by evaluating its impact on Random Blood Glucose (RBG), Fasting Blood Glucose (FBG), and Glycosylated Hemoglobin (HbA1c) levels. Methods: The study was carried out over five months at the Diabetic Clinic of Benazir Bhutto Hospital, Rawalpindi, involving 60 patients (30 males and 30 females) aged 35 to 60 years, selected through convenience sampling based on inclusion criteria. Patients were given 1/2 teaspoon of bitter melon powder daily before breakfast. The patients followed a sugar-free, low-fat diet, and blood glucose levels were measured through biochemical tests before and after the intervention. Data analysis and statistical validation were conducted using ANOVA. Results: The treatment group showed a significant reduction in RBG (244.43 to 201.20 mg/dl, P=0.001) compared to an increase in the control group (246.63 to 275.10 mg/dl, P=0.005). FBG decreased in the treatment group (11.21 to 10.43 mg/dl, P=0.02), while the control group slightly increased (11.21 to 11.26 mg/dl, P=0.10). HbA1c levels also dropped in the treatment group (8.09 to 7.62%, P=0.01) versus a rise in the control group (8.02 to 8.14%, P=0.09). Conclusions: The findings indicate that bitter melon supplementation can significantly lower blood glucose levels and provide a safe alternative to conventional diabetes treatments. Bitter melon, Diabetes mellitus, Alternative medicine, Insulin resistance. 272 281 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1204-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/11 1403/6/21 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/18 1403/10/29 Maria Khalid Institute of Food and Nutritional Sciences, Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi, Pakistan gemini14khalid@gmail.com No Hafiz Muhammad Arslan Ghous Department of Food Science and Technology, School of Food and Agricultural Sciences, University of Management and Technology Lahore, Pakistan arslan.ghous@umt.edu.pk Yes Hafiz Muhammad Rizwan Abid Department of Food Science and Technology, School of Food and Agricultural Sciences, University of Management and Technology Lahore, Pakistan rizwan.abid@umt.edu.pk No

en Background: The production and use of any food must be done according to existing national and international standards. This study aims to investigate the chemical and microbiological properties of flour samples in Hamadan province of Iran. Methods: The results of microbial and chemical tests of 432 flour samples were collected in one of the partner Institute of Standards and Industrial Research of Iran in Hamadan city, and after sorting the data, it was entered into the relevant statistical software and analyzed with appropriate statistical tests. The results were compared with the existing national standards to determine their quality. The evaluated parameters include chemical parameters such as pH, protein, gluten, moisture, and ash) and microbial (mold and total viable count (TVC)). All of the parameters were assessed by the AOAC method. Results: The samples had a higher total count of microorganisms than the standard limit set by the Iran National Standards Organization (INSO). The mean value of chemical parameters (pH, protein, gluten, moisture, and ash) were in the national standard ranges. The results of the present study showed that the level of contamination of the samples was according to the national standards, which could pose no risk to consumers' health. Conclusions: The results of the microbial and chemical tests were within the Institute of Standards and Industrial Research of Iran. The results of the present study can be used by health authorities to evaluate flour quality across Iran and design further investigations on food products. Chemical, Microbial, Flour, National standard,Food safety 282 291 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1198-2&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/112024/09/5 1403/6/15 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/182024/12/21 1403/10/1 Mehdi Ahmadi Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran mehdi.ahmadi9271@yahoo.com Yes Maedeh Jabarzadeh Marand Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran maedeh.jabarzadeh.m@gmail.com No Fatemeh Khajeh Department of Environmental Health Engineering, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran Fatemehkhajeh7070@gmail.com No Seyedeh Maryam Mirsharifi Department of Food Science and Technology, School of Nutrition and Food Science, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran missmirsharifi@gmail.com No Yousef Khaledian Department of Food Hygiene and Quality Control, Faculty of Veterinary, Shahrekord University, Shahrekord, Iran mahdi.ahmadii9271@gmail.com No Reza Hazrati Raziabad Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hazratirezaa@yahoo.com No Mohadeseh Pirhadi Food Safety & Hygiene Division, Department of Environmental Health Engineering, School of Public Health Tehran University of Public Health, Tehran, Iran mehdi.ahmadi@sbmu.ac.ir No

en Background: Thailand is one of the countries facing a high prevalence of low bone mineral density (BMD) due to inadequate calcium (Ca) intake. Using crickets as alternative protein sources is fascinating for nutritionists because of their high biological value and cost-efficient production. This study aims to investigate the effectiveness of Ca-fortified Thai traditional crackers using cricket protein. Methods: Four formulas of Ca-fortified crackers were prepared with different amounts of Ca based on the percentage of recommended Ca in adults for one portion (15%, 25%, and 50% per 250 mg of cracker dough) before conducting a sensory evaluation with 30 participants. The selected acceptable Ca-fortified cracker formula (50% of Ca by RDA per portion) was further used in an intervention study with another group of 40 participants (intervention group=20 and control group=20). The participants in the intervention group were asked to consume 250 g of crackers/day of 50% of RDA per portion formula for 12 weeks to compare bone health parameters with the control group. Results: Results revealed that BMD values of wrist and ankle bones in the intervention group were significantly higher than those in the control group (P=0.004 and P<0.001, respectively), and alkaline phosphatase (ALP) levels in the intervention group were significantly lower than those in the control group (P=0.04) at endpoint. The results also found a positive correlation between Ca intake and BMD parameters among all participants (P<0.001). Conclusion: The developed Ca-fortified Thai traditional crackers using cricket protein is preliminarily effective in improving bone health conditions among the participants. Bone density, Calcium, Food, Cricket, Bone health 292 302 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1041-2&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/112024/09/52024/09/25 1403/7/4 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/182024/12/212025/01/18 1403/10/29 Sasithorn Kosrisuwan Nutrition and Dietetics Division, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand No Samapon Sriwanich Nutrition and Dietetics Division, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand No Suphitsara Aipirome Nutrition and Dietetics Division, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand No Apinya Aurareesuksakul Nutrition and Dietetics Division, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand No Lukkamol Prapkree Sodexo at the University of Kansas Health System: Olathe Campus, Kansas, USA. No Alongkote Singhato Nutrition and Dietetics Division, Faculty of Allied Health Sciences, Burapha University, Chonburi, Thailand alongkote@go.buu.ac.th 0000-0002-5871-3084 Yes

en Background: Veterinary drug residues in poultry products pose significant public health hazards such as cancer, mutagenicity, reproduction challenges and hypersensitivity reactions.  Therefore, this study aimed to investigate the occurrence of some antibiotics and zeranol hormone residues in fresh chicken wings, and also study the effect of heat treatmentes on the concentration of these residues. Methods: Sixty samples of chicken wings were collected from different local markets in Cairo and Giza governorates, Egypt, and were divided into two groups (30 samples for each group) for antibiotics and hormonal residues investigations by high performance liquid chromatography (HPLC) and Enzyme-linked Immune Sorbent Assay (ELISA), respectively. The study was extended to include some cooking methods (boiling, deep frying, and grilling) as types of heat treatments for the reduction of these residues in chicken wings meals and their effects on cooking characteristics, pH, and texture profile. Results: The results revealed that 13.3% of samples were contaminated with ciprofloxacin, tetracycline, and amoxicillin antibiotics residues; however, zeranol hormone was detected in 73.7% of samples. Furthermore, boiling was the most effective method in the reduction of all residues concentrations. Cooking loss, hardness, springiness, cohesiveness, gumminess, and resilience in the examined samples significantly decreased by boiling compared to other two methods. Conclusion: Cooking methods can successfully reduce the concentration of veterinary drugs in chicken wings meals and boiling method was more effective in reducing their concentration. Antibiotics, Chicken wings, Cooking procedures, Zeranol, Residues. 303 314 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1002-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/112024/09/52024/09/252023/09/11 1402/6/20 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/182024/12/212025/01/182024/01/21 1402/11/1 Marwa A. Sheir Department of Special Food and Nutrition, Food Technology Research Institute, Agricultural Research Center, Giza, Egypt marwa.sheir@yahoo.com 0000-0001-7377-6107 Yes Nesrin Saad Eldin Mohammed Department of Meat and Fish Technology Research, Food Technology Research Institute, Agricultural Research Center, Giza, Egypt nesrin.bondok@yahoo.com No Mona Momtaz Mohammad Abd-elaziz Department of Food Hygiene, Animal Health Research Institute, Agricultural Research Center- -Giza, Egypt. d.monamomtaz@hotmail.com No

en Background: Type 2 diabetes mellitus (T2DM) is considered a problem for public health worldwide and cardamom (Elettaria cardamomum) as a spice which contains polyphenolic components may have a beneficial effect on the status of diabetes patients. This systematic review and meta-analysis aims to update the efficacy of cardamom intake on weight reduction and glycemic control. Methods: Electronic databases were searched up to December 2023 to identify eligible articles. Mean differences were pooled using a fixed effects model, and standard methods were used for the assessment of heterogeneity, sensitivity analysis, and publication bias. Results: Totally, eight studies were included in the final analysis. Analysis showed that cardamom intake attenuated serum level of insulin [standard mean difference (SMD): -0.64, 95% CI: -0.86 to -0.43, P<0.001], whereas changes of fasting blood glucose (SMD: -0.13, 95% CI: -0.33 to 0.06), weight (SMD: -0.01, 95% CI: -0.23 to 0.20) and body mass index (SMD: -0.05, 95% CI: -0.02 to 0.11) were not significant. Conclusion: According to the findings of the present meta-analysis, cardamom intake significantly declined serum insulin level but did not have any significant effect on fasting blood glucose, weight, and body mass index. Cardamom, Anthropometric, Glycemic, Meta-analysis. 315 327 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1171-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/112024/09/52024/09/252023/09/112024/08/3 1403/5/13 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/182024/12/212025/01/182024/01/212024/10/21 1403/7/30 Omid Nikpayam Department of Nutrition, School of Health, Golestan University of Medical Sciences, Gorgan, Iran nikpayamomid@gmail.com 0000-0002-6301-1597 No Golbon Sohrab Clinical Nutrition and Dietetics Department, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran golbonsohrab@yahoo.com 0000-0002-3348-2734 No Marziyeh Najafi Clinical Nutrition and Dietetics Department, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran mnajafi284@gmail.com 0009-0006-0643-0011 No Shahab Papi Research Center for Social Factors Affecting Health, Faculty of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran shahabpapi@yahoo.com 0000-0001-9917-7364 No Alireza Ostadrahimi Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran ostadrahimi@tbzmed.ac.ir 0000-0002-1058-1481 Yes

en Background: The current data on the association between dietary polyphenols intake and liver cancer are not conclusive. Therefore, we aimed to perform a systematic review and meta-analysis of observational studies on the association between dietary polyphenol intake and liver cancer. Methods: A systematic search of online databases, including PubMed/MEDLINE, Scopus, and Web of Science, was conducted until August 2024. Observational studies that investigated the association between dietary intake of polyphenols and the risk of liver cancer were included. The overall effects were assessed using the random effects model. Results: Totally, four studies were eligible to be included in the systematic review, and for meta-analysis, 3 studies with 4 effect sizes were included. The overall association between dietary intake of isoflavones and the risk of liver cancer was not significant (P=0.35, 95% CI: 0.58-1.21). Conclusion: No significant association was found between dietary polyphenols intake and liver cancer risk. Further observational studies are suggested to confirm these findings. Polyphenols, Isoflavones, Liver neoplasms, Hepatocellular cancer. 328 337 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-1131-1&slc_lang=en&sid=1 2024/05/172024/06/92024/10/282024/09/72023/12/292024/11/62024/05/302024/11/92024/09/112024/09/52024/09/252023/09/112024/08/32024/05/31 1403/3/11 2024/09/212024/09/212025/02/152024/12/122024/09/212023/02/212024/10/212025/01/212025/01/182024/12/212025/01/182024/01/212024/10/212024/10/18 1403/7/27 Arezoo sadat Emrani Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran arezooemrani.ae@gmail.com 0000-0002-2909-3314 No Fatemeh Mirjalili Research Center for Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran mirjalilifatemeh1372@gmail.com 0000-0003-1130-6294 No Hooman Yekrang Safakar Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran loodvik_hys@yahoo.com 0009-0004-41231-6675 No Bita Forootani Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran bita.frt@gmail.com 0009-0001-8598-2714 No Amin Salehi-abargouei Yazd Cardiovascular Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran abargouei@gmail.com 0000-0002-7580-6717 Yes