Journal of Nutrition and Food Security

en Selenium Concentrations in Patients with Depression: A Case-Control Study public specific orginal article <div style="text-align: justify;"> Evidence suggests that dietary micronutrients may be associated with depression. The role of selenium as a risk or protective factor for depression was contradictory. Therefore, this study aimed to investigate the association between serum selenium concentrations and depression. Methods: This case-control study was conducted from 2018 to 2020 in Shahrekord, Iran. The case and control groups included patients with or without depression, respectively. Seventy-two participants were selected using the conventional method. In addition to recording demographic variables, the blood selenium concentration of the participants was measured. Results: There was no difference between case and control groups in terms of mean levels of blood selenium (P>0.05). Results showed that there was no statistically significant interaction between the effects of gender and group (P=0.51), age and group (P=0.13), Body mass index (BMI) and group (P=0.52) on blood selenium concentrations. However, females had significantly more selenium concentrations than males in both groups (P=0.005). Conclusion: Despite some confirming evidence for the association of depression and blood selenium concentration, this study did not show such a relationship. However, blood selenium concentration was higher in women than men in both groups.</div>   Selenium, Depression, Patients, Iran, Case-control studies 52 58 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-585-1&slc_lang=en&sid=1 Elham Zarean 0000-0001-7294-6709 No Department of Psychiatry, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran Pardis Sadeghi 0000-0001-9306-8351 No Clinical Research Development Unit, Hajar Hospital, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran Tina Jafari 0000-0001-7262-0135 No Social Determinants of Health Research Center, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran Afsaneh Malekpour Tehrani https:/0000-0001-6599-9028 No Department of Community Medicine, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran Samaneh Torkian Torkiansamane72@gmail.com 0000-0002-7913-2801 Yes Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.