en public specific editorial article <div class="WordSection1"> <div> <table align="left" hspace="0" vspace="0"> <tbody> <tr> <td align="left" style="padding-top:0in; padding-right:0in; padding-bottom:0in; padding-left:0in" valign="top"></td> </tr> </tbody> </table> </div> </div> <div><div aria-label="Page Break" class="cke_pagebreak" data-cke-display-name="pagebreak" data-cke-pagebreak="1" style="page-break-after:always" title="Page Break" contenteditable="false"></div><span style="font-size:11.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">some studies have suggested that vitamin C deficiency may play a role in the etiology of depression although the efficient dose and time of prescription is not clear now. &nbsp;Also, it is not known which antidepressant drugs could be more efficient in augmentation with vitamins. Nowadays, due to the importance and more prevalence of psychiatric disorders, dietary supplements which would augment the effects of drugs have been taken into consideration. Moreover, dose titration of anti-depressant drugs is a lifelong challenge due to unwanted side effects</span></span></span></div> Vitamin C, Ascorbic Acid, Depression 152 154 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-104-2&slc_lang=en&sid=1 Reza Bidaki 0000-0002-5482-9143 No Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; Mahsa Mahdavi Firoozabadi 0000-0002-9253-6720 No Research center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mahsa Motamed 0000-0001-6550-8292 Yes Department of Psychiatry, Residence of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Sina Taherzadeh Borujeni 0000-0003-0989-519X No Department of Psychiatry, Psychiatrist, Tehran University of Medical Sciences, Tehran, Iran Azadeh Nadjarzadeh 0000-0002-9740-8402 No Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.