en public specific orginal article <pre> <strong>Background</strong><strong>:</strong> The purpose of this study was to investigate the effect of an eight-week combined exercise training program with sweet almond supplementation on plasma levels of leptin and orexin in overweight women. <strong>Methods:</strong> This research was a quasi-experimental study. <a name="OLE_LINK198"></a><a name="OLE_LINK197">The statistical population consisted of 60 </a>overweight <a name="OLE_LINK200"></a><a name="OLE_LINK199">women with a body mass index (BMI) of 25-30</a> kg/m² who were <a name="OLE_LINK202"></a><a name="OLE_LINK201">randomly divided into </a><a name="OLE_LINK469"></a><a name="OLE_LINK468">four groups of training, </a><a name="OLE_LINK519"></a><a name="OLE_LINK518">training-sweet almond supplement, supplement</a>, and control. <a name="OLE_LINK220"></a><a name="OLE_LINK219"></a><a name="OLE_LINK218"></a><a name="OLE_LINK217"></a><a name="OLE_LINK216">The </a>participants participated in <a name="OLE_LINK483"></a><a name="OLE_LINK482">three training sessions </a><a name="OLE_LINK18"></a><a name="OLE_LINK19">weekly</a> <a name="OLE_LINK226"></a><a name="OLE_LINK225">and consumed sweet almond supplementation </a>for eight consecutive weeks. <a name="OLE_LINK523"></a><a name="OLE_LINK522"></a><a name="OLE_LINK31"></a><a name="OLE_LINK32"></a><a name="OLE_LINK29"></a><a name="OLE_LINK30"></a><a name="OLE_LINK235"></a><a name="OLE_LINK234">The participants&#39; blood samples were taken</a> 24 hours before the first session and after the last session, in a <a name="OLE_LINK237"></a><a name="OLE_LINK236">12-hour fasting state</a>. <a name="OLE_LINK239"></a><a name="OLE_LINK238">Liptin concentrations were </a>measured using <a name="OLE_LINK245"></a><a name="OLE_LINK244">Pishtaz Teb Inc. </a>kits. <a name="OLE_LINK531"></a><a name="OLE_LINK530"></a><a name="OLE_LINK247"></a><a name="OLE_LINK246"></a><a name="OLE_LINK241"></a><a name="OLE_LINK240">Orexin levels </a>were determined through <a name="OLE_LINK251"></a><a name="OLE_LINK250">enzymatic method</a> using the <a name="OLE_LINK243"></a><a name="OLE_LINK242">Virro Inc. kit</a>. <a name="OLE_LINK541"></a><a name="OLE_LINK540">A two-way repeated measures ANOVA </a>was conducted to analyze the inter- and intra-group variance. The overall alpha significance level was set at P &le; 0.05 for all the statistical analyses. <strong>Results:</strong> Eight weeks of combined exercise training with sweet almond supplementation Showed a significant reduces in serum level leptin concentration and increased the plasma orexin levels. <strong>Conclusion:</strong> According to the results of the present study It can be used from combined training and sweet almonds to reduce appetite and lose weight in overweight women.</pre> Combined exercise training, Sweet almond supplementation, Leptin, Orexin, Overweight women 218 224 http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-152-1&slc_lang=en&sid=1 Farideh Afkhami 0000-0003-0796-6126 No Department of Physical Education, Yazd Branch, Islamic Azad University, Yazd, Iran Abbas Fattahi Bafghi abbasfb60@gmail.com 0000-0003-0519-3262 Yes Department of Physical Education, Bafgh Branch, Islamic Azad University, Bafgh, Iran. Hamid Abbasi Bafghi 0000-0002-1037-6453 No Department of Physical Education, Yazd University, Yazd, Iran.