Background: The instinct and natural tendency to eat food is an undeniable fact in human and all human beings, even the messengers of Allah and Infallible Imams (A.S) need it in order to keep themselves healthy. Methods: In this review study, using the teachings of the Holy Quran and other Islamic texts, the importance and role of food and healthy nutrition and its role in elevating human beings have been collected. Results: Formally, one of the influential factors in maintaining human’s physical and mental health is his food and maintaining human health to preserve his real perfection and his unique position and dignity among creatures is mostly based on pure and healthy food. Allah has considered all human aspects in the Holy Quran, the book of human guidance and prosperity, and not neglecting, for example, his need of food, he has offered some guidance to meet this need. The Quran’s criteria for choosing food are its lawfulness and purity. Conclusion: Considering the fact that “pure” means being pleasurable and good to eat, one of the interpretations offered in this article is that the man should avoid eating foods that are against human nature due to its being inconsistent with intact divine nature of human.