In a diet, probiotics and prebiotics play an important role in regulating the immune response function through the intestinal microbiota, which in turn affects the immune system. While probiotics have been shown to reduce diseases, such as the flu, which is a respiratory infection. The National Health Commission of China and the National Bureau of Traditional Medicine of China recommend that probiotics be used in acute patients with COVID-19 to prevent secondary bacterial infection (Antunes et al., 2020, Anwar et al., 2020).