Volume 4, Issue 1 (Feb 2019)                   JNFS 2019, 4(1): 7-16 | Back to browse issues page


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Shahzeidi M, Nadjarzadeh A, Rahmanian M, Salehi Abargouei A, Fallahzadeh H, Mogibian M et al . The Effect of Oat Bran Supplement on Fasting Blood Sugar and Glycosylated Hemoglobin in Patients with Gestational Diabetes Mellitus: Single-blind Randomized Clinical Trial. JNFS 2019; 4 (1) :7-16
URL: http://jnfs.ssu.ac.ir/article-1-232-en.html
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (3875 Views)
Background: Gestational diabetes mellitus (GDM) is known as a degree of glucose intolerance that occurs for the first time during pregnancy. There is paucity of evidence regarding the effect of oat bran on GDM. Oat as a source of β-glucan can be effective in reducing the blood sugar levels. This study aimed to investigate the effect of oat bran on fasting blood sugar (FBS) and glycosylated hemoglobin (HbA1c) in patients with GDM. Method: This single-blind clinical trial was conducted on 90 pregnant women with GDM. The experimental group (EG) consumed 30 g of oat bran daily with 100 g of low-fat yogurt before lunch and dinner for 4 weeks. The control group (CG) consumed only low-fat yogurt and both groups received nutrition counseling. The present study investigated the FBS, HbA1c, and weight gain at the beginning and after four weeks of intervention. Results: Out of 90 patients, 80 completed the study. FBS decreased in the EG (P = 0.04, -2.75 ± 8.22), whereas, it increased in the CG (P = 0.003, 4.37 ± 8.72). No significant difference was observed between the two groups in terms of HbA1c levels. Weight gain was controlled more efficiently in the EG than the CG (P = 0.001). Conclusion: The use of oat bran for four weeks decreased the FBS,; whereas, it did not affect HbA1c levels. Weight gain was controlled better in the EG than the CG.
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Type of article: orginal article | Subject: public specific
Received: 2018/05/13 | Published: 2019/02/1 | ePublished: 2019/02/1

References
1. Acheson KJ 2010. Carbohydrate for weight and metabolic control: where do we stand? Nutrition. 26 (2): 141-145.
2. Afaghi A, Ghanei L & Ziaee A 2013. Effect of low glycemic load diet with and without wheat bran on glucose control in gestational diabetes mellitus: A randomized trial. Indian journal of endocrinology and metabolism. 17 (4): 689.
3. Afaghi A, et al. 2011. Effect of wheat bran on postprandial glucose response in subjects with impaired fasting glucose. Current topics in nutraceuticals research. 9 (1/2): 35.
4. Asemi Z, Tabassi Z, Samimi M, Fahiminejad T & Esmaillzadeh A 2013. Favourable effects of the Dietary Approaches to Stop Hypertension diet on glucose tolerance and lipid profiles in gestational diabetes: a randomised clinical trial. British journal of nutrition. 109 (11): 2024-2030.
5. Association AD 2014. Diagnosis and classification of diabetes mellitus. Diabetes care. 37 (Supplement 1): S81-S90.
6. Battilana P, et al. 2001. Mechanisms of action of beta-glucan in postprandial glucose metabolism in healthy men. European journal clinica nutrition. 55 (5): 327-333.
7. Bellamy L, Casas J-P, Hingorani AD & Williams D 2009a. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet (London, England). 373 (9677): 1773-1779.
8. Bellamy L, Casas JP, Hingorani AD & Williams D 2009b. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet (London, England). 373 (9677): 1773-1779.
9. Berg A, et al. 2003. Effect of an oat bran enriched diet on the atherogenic lipid profile in patients with an increased coronary heart disease risk. Annals of nutrition and metabolism. 47 (6): 306-311.
10. Boulet SL, Alexander GR, Salihu HM & Pass M 2003. Macrosomic births in the united states: determinants, outcomes, and proposed grades of risk. American journal of obstetrics and gynecology. 188 (5): 1372-1378.
11. Braaten J, et al. 1994. High β‐Glucan Oat Bran and Oat Gum Reduce Postprandial Blood Glucose and Insulin in Subjects With and Without Type 2 Diabetes. Diabetic medicine. 11 (3): 312-318.
12. Brand-Miller J, Hayne S, Petocz P & Colagiuri S 2003. Low-glycemic index diets in the management of diabetes: a meta-analysis of randomized controlled trials. Diabetes care. 26 (8): 2261-2267.
13. Brennan CS 2005. Dietary fibre, glycaemic response, and diabetes. Molecular nutrition & food research. 49 (6): 560-570.
14. Chen J & Raymond K 2008. Beta-glucans in the treatment of diabetes and associated cardiovascular risks. . Vascular health and risk management. 4 (6): 1265.
15. Cugnet-Anceau C, et al. 2010. A controlled study of consumption of beta-glucan-enriched soups for 2 months by type 2 diabetic free-living subjects. British journal nutrition. 103 (3): 422-428.
16. Denyer G 1998. Dietary carbohydrate and insulin resistance: lessons from humans and animals. In Proceeding-NUnutrition society of Australia, pp. 158-167. NUnutrition society of Australia.
17. Gilmartin AB, Ural SH & Repke JT 2008. Gestational diabetes mellitus. Reviews in obstetrics and gynecology. 1 (3): 129-134.
18. Group I 2006. International Physical Activity Questionnaire. Guidelines for data processing and analysis of the international physical activity guidelines.
19. Gunderson EP, et al. 2014. History of gestational diabetes mellitus and future risk of atherosclerosis in mid-life: the Coronary Artery Risk Development in Young Adults study. Journal of American heart association. 3 (2): e000490.
20. Gupta P, Narang M, Banerjee BD & Basu S 2004. Oxidative stress in term small for gestational age neonates born to undernourished mothers: a case control study. BMC pediatrics. 4 (1): 14.
21. He LX, Zhao J, Huang YS & Li Y 2016. The difference between oats and beta-glucan extract intake in the management of HbA1c, fasting glucose and insulin sensitivity: a meta-analysis of randomized controlled trials. Food & function. 7 (3): 1413-1428.
22. Hernandez-Cordero S, Neufeld LM, Garcia-Guerra A & Aburto NJ 2008. Physical activity during pregnancy and early postpartum in Mexican women. Federation of American societies for experimental biology (FASEB) journal. 22 (1): 679.673.
23. Jarmuzek P, Wielgos M & Bomba-Opon D 2015. Placental pathologic changes in gestational diabetes mellitus. Neuro enocrinology letters. 36 (2): 101-105.
24. Jonsdottir SS 2009. Hyperglycemia and Adverse Pregnancy Outcomes. American journal of maternal/child Nnrsing. 34 (4): 266.
25. Kabir M, et al. 2002. Four-week low-glycemic index breakfast with a modest amount of soluble fibers in type 2 diabetic men. Metabolism. 51 (7): 819-826.
26. Kerckhoffs DA, Hornstra G & Mensink RP 2003. Cholesterol-lowering effect of β-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when β-glucan is incorporated into bread and cookies. American journal of clinical nutrition. 78 (2): 221-227.
27. Lim SS, Noakes M & Norman RJ 2007. Dietary effects on fertility treatment and pregnancy outcomes. Current opinion in endocrinology, diabetes and obesity. 14 (6): 465-469.
28. Liu S, et al. 2003. Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women. American journal of clinical nutrition. 78 (5): 920-927.
29. Lovegrove JA, Clohessy A, Milon H & Williams CM 2000. Modest doses of β-glucan do not reduce concentrations of potentially atherogenic lipoproteins. American journal of clinical nutrition. 72 (1): 49-55.
30. McGowan CA & McAuliffe FM 2010. The influence of maternal glycaemia and dietary glycaemic index on pregnancy outcome in healthy mothers. British journal of nutrition. 104 (02): 153-159.
31. Metzger B, et al. 2010. International Association of Diabetes and Pregnancy Study Groups Consensus Panel. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes care. 33 (3): 676-682.
32. Metzger BE, et al. 2008. Hyperglycemia and adverse pregnancy outcomes. New England journal of medicine. 358 (19): 1991-2002.
33. Moghaddam M, et al. 2012. The Iranian Version of International Physical Activity Questionnaire (IPAQ) in Iran: content and construct validity, factor structure, internal consistency and stability. World applied sciences journal. 18 (8): 1073-1080.
34. Montminy C & Galibois I 1994. Role of protein and fiber-source nature on glucose metabolism in rats. Nutrition. 10 (2): 144-150.
35. Moreno-Castilla C, Mauricio D & Hernandez M 2016. Role of medical nutrition therapy in the management of gestational diabetes mellitus. Current diabetes reports. 16 (4): 1-9.
36. Muktabhant B, Lawrie TA, Lumbiganon P & Laopaiboon M 2015. Diet or exercise, or both, for preventing excessive weight gain in pregnancy. Cochrane database of systematic reviews. 6: Cd007145.
37. Pick ME, et al. 1996. Oat bran concentrate bread products improve long-term control of diabetes: a pilot study. Journal of the American dietetic association. 96 (12): 1254-1261.
38. Porikos KP, Hesser MF & Van Itallie TB 1982. Caloric regulation in normal-weight men maintained on a palatable diet of concentional foods. Physiology & behavior. 29 (2): 293-300.
39. Raninen K, Lappi J, Mykkänen H & Poutanen K 2011. Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose. Nutrition reviews. 69 (1): 9-21.
40. Rebello CJ, et al. 2013. Acute effect of oatmeal on subjective measures of appetite and satiety compared to a ready-to-eat breakfast cereal: a randomized crossover trial. Journal of the American college of nutrition. 32 (4): 272-279.
41. Reyna NY, et al. 2003. Sweeteners and beta-glucans improve metabolic and anthropometrics variables in well controlled type 2 diabetic patients. American journal of therapeutics. 10 (6): 438-443.
42. Ripsin CM, et al. 1992. Oat products and lipid lowering. A meta-analysis. Journal of the American medical association 267 (24): 3317-3325.
43. Roberts SB & Heyman MB 2000. Dietary composition and obesity: do we need to look beyond dietary fat? Journal of nutrition. 130 (2S Suppl): 267s.
44. Robitaille J, Fontaine-Bisson B, Couture P, Tchernof A & Vohl MC 2005. Effect of an oat bran-rich supplement on the metabolic profile of overweight premenopausal women. Annals of nutrition and metabolism. 49 (3): 141-148.
45. Tapola N, Karvonen H, Niskanen L, Mikola M & Sarkkinen E 2005. Glycemic responses of oat bran products in type 2 diabetic patients. Nutrition, metabolism & cardiovascular diseases. 15 (4): 255-261.
46. Tappy L, Gügolz E & Würsch P 1996. Effects of breakfast cereals containing various amounts of β-glucan fibers on plasma glucose and insulin responses in NIDDM subjects. Diabetes care. 19 (8): 831-834.
47. Viana LV, Gross JL & Azevedo MJ 2014. Dietary intervention in patients with gestational diabetes mellitus: a systematic review and meta-analysis of randomized clinical trials on maternal and newborn outcomes. Diabetes care. 37 (12): 3345-3355.
48. Wang X, Liang L, Junfen F & Lizhong D 2007. Metabolic syndrome in obese children born large for gestational age. Indian journal of pediatrics. 74 (6): 561-565.
49. Wei JN, et al. 2007. Birth weight correlates differently with cardiovascular risk factors in youth. Obesity. 15 (6): 1609-1616.
50. Whitehead A, Beck EJ, Tosh S & Wolever TM 2014. Cholesterol-lowering effects of oat beta-glucan: a meta-analysis of randomized controlled trials. American journal of clinical nutrition. 100 (6): 1413-1421.
51. Wood P, Beer M & Butler G 2000. Evaluation of role of concentration and molecular weight of oat β-glucan in determining effect of viscosity on plasma glucose and insulin following an oral glucose load. British journal of nutrition. 84 (01): 19-23.
52. Wood PJ 2007. Cereal β-glucans in diet and health. Journal of cereal science. 46 (3): 230-238.

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