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Volume 8, Issue 4 (Nov 2023)
JNFS 2023, 8(4): 544-552 |
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Peigan P, Mirzaei M, Marques-Vidal P, Fallahzadeh H, Kraemer A, Sarebanhassanabadi M. Comparison of 5-year Incidence of Type 2 Diabetes in Obese and Non-Obese Adult Population: The YaHs Cohort. JNFS 2023; 8 (4) :544-552
URL: http://jnfs.ssu.ac.ir/article-1-667-en.html
URL: http://jnfs.ssu.ac.ir/article-1-667-en.html
Parisa Peigan 
, Masoud Mirzaei , Pedro Marques-Vidal , Hossein Fallahzadeh , Alexander Kraemer , Mohammadtaghi Sarebanhassanabadi *
, Masoud Mirzaei , Pedro Marques-Vidal , Hossein Fallahzadeh , Alexander Kraemer , Mohammadtaghi Sarebanhassanabadi *
Yazd Cardiovascular Research Center, Non-communicable diseases research institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract: (813 Views)
Background: Obesity is an important predictor of diabetes. Defining the risk of diabetes among obese subjects is important for preventive health strategies. This study aims to compare the 5-year incidence of diabetes in obese and non-obese adult participants aged 20-70 years in a large population sample of central Iran. Methods: In this prospective study, 9964 people aged 20-70 years were selected between 2014 and 2015 using multi-stage cluster sampling from Yazd Greater Area, Iran. Participants with diabetes were excluded and non-diabetic individuals were evaluated for incident diabetes after a five-year follow-up. Logistic regression was used to find the association between obesity and 5-year incidence of diabetes in bivariate, and multivariate adjusted models for age, sex, physical activity, medical history, marital status, smoking, and education. Results: Out of the initial 9964 participants, 1383 (14%) were excluded due to prevalence of diabetes. The remaining 8413 (86.0%) participants were re-examined in 2019-2020. After five years of follow up, diabetes occurred in 6.6% (n=556) of the participants. The incidence of diabetes in obese men and women was 10.4% (n=109) and 9.9% (n=264), respectively; however, it was 4.5% (n=143) and 2.8% (n=40) in their non-obese counterparts (P<0.01). After multivariate analysis, obesity was associated with a higher likelihood of diabetes in men (OR=1.77, 95% CI: 1.33-2.35), women (OR=2.23, 95% CI: 1.55-3.21), and overall (OR=1.99, 95%CI: 1.60-2.48). Similar findings were obtained in participants aged under and over 60 years (P<0.05). Conclusion: There was a positive association between obesity and 5-year incidence of diabetes in an Iranian adult population. Interventions are required to change lifestyle in the adult population especially in younger participants to prevent obesity and diabetes.
Corresponding Author:Mohammadtaghi Sarebanhassanabadi
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Corresponding Author:Mohammadtaghi Sarebanhassanabadi
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Type of article: orginal article |
Subject:
public specific
Received: 2022/07/3 | Published: 2023/11/20 | ePublished: 2023/11/20
Received: 2022/07/3 | Published: 2023/11/20 | ePublished: 2023/11/20
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